PODCAST

 

Zac Stritch-Hoddle speaks with world-renowned researchers and medical professionals to better understand the mysterious link between tick bites and allergic reactions to mammalian products such as beef and pork. What starts with one doctor’s discovery in a small group of people in Sydney, Australia, goes on to implicate everything from vaccine development, cancer treatment, and a revolutionary change in our understanding of how allergies work.

 

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Genetic and molecular insights into dangerous tick bite-related meat allergy revealed.

Providing a framework for future therapeutics development, not only for tick-induced allergies but for other diseases as well.

EPISODE 2 - BEYOND THE BITE: EXPLORING AUTOIMMUNE BREAKTHROUGHS AT THE GARVAN INSTITUTE

In this episode, We speak with Professors Antony Basten and Daniel Christ, as well as Dr David Langley at the Garvan Institute in Sydney, Australia. Where they guide us through the research being done on the alpha-gal molecule and why the Garvan Institute is so interested in understanding it. We talk about everything from how an understanding of alpha-gal could help us better prevent diseases such as malaria, to how tick-induced sensitisation to alpha-gal is associated with increased risk of coronary artery disease.

REFERENCES:

Genetic and structural basis of the human anti-α-galactosyl antibody response

TRANSCRIPT:

Episode #2

Credits:

JANELLE WILLIAMS: EXECUTIVE PRODUCER

ZAC STRITCH-HODDLE & REMY WILLIAMS: PRODUCERS

ZAC STRITCH-HODDLE: PRESENTER

WEEDITPODCASTS.COM: EDITING

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Professor Sheryl van Nunen

First described the association between tick bites and the subsequent development of mammalian meat anaphylaxis, documented the first instance of a proven IgE-mediated mechanism in anaphylaxis to a food (mammalian meat) in systemic mastocytosis and first described ticks as an insect causing anaphylaxis in systemic mastocytosis.

We speak with Professor Sheryl van Nunen to unravel the mystery behind a startling association: a history of tick bites and the subsequent onset of often life-threatening allergic reactions to a sugar known as alpha-gal found in mammalian products such as beef, dairy, and pork. Professor Sheryl van Nunen guides us through the early days of this novel allergy's discovery and the impact this has had on the world. We'll also explore how mammalian meat allergy is unique — it's both preventable and potentially curable. How, you ask? By preventing tick bites and safely removing ticks if you do get bitten. With Professor Sheryl van Nunen's science-backed strategies, this can be easily achieved.

references:

An association between tick bite reactions and red meat allergy in humans

A novel Australian tick Ixodes (Endopalpiger) australiensis inducing mammalian meat allergy after tick bite

Tick killing in situ before removal to prevent allergic and anaphylactic reactions in humans: a cross-sectional study

Immunoglobulin E Sensitization to Mammalian Oligosaccharide Galactose-α-1,3 (α-Gal) Is Associated With Noncalcified Plaque, Obstructive Coronary Artery Disease, and ST-Segment–Elevated Myocardial Infarction

transcript:

Episode #1


Credits:

JANELLE WILLIAMS: EXECUTIVE PRODUCER

ZAC STRITCH-HODDLE & REMY WILLIAMS: PRODUCERS

ZAC STRITCH-HODDLE: PRESENTER

WEEDITPODCASTS.COM: EDITING

 

“Remember Freeze it

Don’t Squeeze it”

Disclaimer:

The "Tick, Tick Boom!" podcast is produced by TiARA.org.au, a non-profit organization dedicated to Tick Induced Allergies Research & Awareness. The information presented in this podcast is intended for informational purposes only and should not be considered medical advice. While we strive to ensure the accuracy of the information provided, the content of this podcast is not intended to diagnose, treat, cure, or prevent any disease or health condition. Listeners are encouraged to consult with qualified healthcare professionals for diagnosis and treatment, especially if experiencing symptoms related to tick-induced allergies or any other medical condition. The views and opinions expressed by the hosts, guests, or individuals appearing on the podcast are their own and do not necessarily reflect the views of TiARA.org.au or its affiliates. Listeners are advised to use discretion when applying any information from this podcast and to always seek the advice of a physician or other qualified healthcare provider with any questions or concerns regarding a medical condition. By listening to this podcast, you agree to these terms and acknowledge that TiARA.org.au and its representatives are not responsible for any actions taken based on the information presented during the podcast.